The load average is to high and the cpu time used by the system is to high, too.
In this case it there are no more possibilities make MySQL running faster with tuning buffer values. There are some other
indices needed.
A few more indices and a key buffer with an eqal size - will make it perfect.
The swap space is used every time, a MySQL process is to "old": Linux thinks it could be swapped out.
If the MySQL processes have a shorter life time, because of the faster answering behaviour to the queries, there is no more need to swap out for Linux.